Pentostatin FDA Link Generic

A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.

Also Known As:

Nipent; CI-825; Co-Vidarabine; Deoxycoformycin; Imidazo(4,5-d)(1,3)diazepin-8-ol, 3- (2- deoxy- beta- D- erythro- pentofuranosyl)- 3,4,7,8- tetrahydro- , (R)-; NSC-218321; 2' Deoxycoformycin; CI 825; CI825; NSC 218321; NSC218321; 2'-Deoxycoformycin; Imidazo(4,5-d)(1,3)diazepin-8-ol, 3- (2- deoxy- D- erythro- pentofuranosyl)- 3,4,7,8- tetrahydro- , (8R)-

Pharmalogical Action Categories:

Adenosine Deaminase Inhibitors
Antineoplastic Agents

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Formycins: 1
        Coformycin: 7
        Pentostatin: 512
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Formycins: 1
      - Coformycin: 7
        Pentostatin: 512
  - Deoxyribonucleosides: 34
    - Pentostatin: 512

R P McCaffrey Selected Research

R P McCaffrey Research Topics

Disease

Drug/Important Bio-Agent (IBA)